Enjoying Xmas and severe scabbies at home

http://onlinelibrary.wiley.com/enhanced/doi/10.1111/j.1365-3024.2010.01218.x/

getting into remission, possibly risked, see the above, my wife is basically bed ridden by severe scabbies, a truly rare and debilitating disease.

I have proposed intense german immunotherapies, as this too like cancer our recovery and quality of life depends on our white cells. I sound racist in my adoration of these cells and western medicine ignorance of there management.

My daughter has them as well, putting the kids, on far infared sauna, ahcc, gcmaf maf 314 yogurt. do you get the irony, i have been making it, have been forcing my wife to have it, i go to germany. save my ass again and come home and her condition is now critical, her agony still does not allow her to clear or clean her rubbish. ourbed room now uninhabitable, especially to a husband with so many immunotherapies working that i am blessed.

DO YOU GET THE IRONY, I LEAVE, SHE STOPS MAF 314 YOGURT, HER SCABBIES THATS BEEN MANAGED, EXPLODES TO THE MOST SEVERE FORM, IN JUST 2 WEEKS. EVEN MY MOTHER, MY WIFE WANT BELIEVE IN THE YOGURT, THIS AMAZES ME.

MY KIDS ARE SCARED OF THE PAIN AND DISFIGUREMENT THAT CAN COME FROM THE SEVEREST FORM OF THIS DISEASE, THEY WILL TAKE THE YOGURT, MADE ANOTHER BATCH TODAY, I AM A GCMAF PROBIOTIC YOGURT FACTORY. BUY IT FROM BRAVO PROBIOTICS, TELL THEM PETE REFERRED YOU, NOT THAT i GET A CENT, BUT MAYBE ONE DAY. ONE DAY THE STRAINS WILL BE FREE, THEY ARE FOR THE POOREST AND THE MOST NEEDY IN TANZANIA

http://events.tru.ca/event/2014/using-probiotic-yogurt-improve-outcomes-pregnant-tanzanian-women

http://www.nature.com/nm/journal/v15/n6/full/nm0609-594.html

http://www.thebody.com/content/art52570.html must read!!!!!!!!!!!!!!!!!!!!!!!!!!
AM I NOT THE MOST BLESSED CANCER PATIENT ON THE PLANET ?
The sincerest thanks to Prof Ruggiero and his stunning wife. Noones yogurt cultures have travelled the planet or germany, or australia like mine. An achievement I am so proud of, if you my customer, thank God with every mouthful, saviour the yogurt, leave it in your mouth, feel your tonsilar macrophages being activated. YOU SIMPLY MUST BELIEVE, FAITH IS THE KEY, BUT THEN YOU NEED THE YOGURT.

MY SYSTEM WORKS! GOD THIS IS EXCITING, EVERY SIGNLE THING I DO IS BASED ON SCIENCE!

i am finding some new patients, and have embraced my new companies mission to deliver the same cutting edge innovative therapies and combinations with extreme lifestyle interventions.

I am an entreprenuer, i cannot spell, i can employ. If i can save one life, well i can save another, noone knows what i do and how i do it. maybe my lack of clarity has in the end served a nobel commercial purpose, I deserve and obliged to commercial my success.

Hint the profit, has been been in the drugs, while the world chases drugs like ipilimimab, i chase aggressive meditation peacefully, diet, exercise and love. Add to these the worlds bravest and cleverest doctors. Not blindfolded and handcuffed western jerks driving porches.

Just ask your doctor about clear metastatic success rates ?and then call me!

My time helping and caring for my wife, to take the kids to xmas parties and shopping and movies and have some pretty serious talks.

It took 1/2 day to clear and clean the kitchen to be able to make breakfast, i made the kids help clean.

I relish my health and strength and focus, life is so good due to its challenges, not despite them.

Personally I find metastatic cancer easy in comparision to mental illness.

Love, charity and hope are in this home, and one present for the kids, ME! ok they also get a sony tablet to share.

To be alive is bliss, everyone loves shopping, i pointed out to the kids, how empty the prayer room was at the airport and how busy the shops. The shoppers want find true love and peace in possessions, my anto possession approach the result of living many years with a hoarder made worse by a stage 4 colorectal cancer and so many recurrences, that thanks be to God each disappear. Its as if God is teaching me how to clear each organ system in the body!

MY XMAS PRAYER

Dear Lord,
Please continue to grant me further success, success for myself, my family and all my friends!
Help me to understand and unlock your healing power with all the therapies I have access too.
Grant me the wisdom and the guidance to help all my cancer friends, especially those who you send to me
forpersonalised guidance. I absolutely need your help, to motivate and give hope,
to the terminal cancer patients told lies by conventional medicine,
to the doctors who remain willfully ignorant of your greatest medical gifts,
give and grant my doctors the courage and insight to deliver your miracles.
thank you for the gift of this life and all that is in it,
For existence with you is bliss, it is truly is.
A life based on your power, is full of love, not fear!
Give us all the courage, the strength and the peace to prevail.
Thank you for every challenge, which are your greatest gifts.
These lessons I seek to understand and share.
Give my newest friends, seeking there miracles the deepest faith in you.
Help us, to help ourselves, you have given us what we need, as the birds.
Let us ALL shine as examples of your power and this medicine.
Grant my mother eternal peace and welcome to her into heaven!
Grant the bank approval of my $1,000,000 loan, a success valuation on Xmass even, this will fund
the most innovative cancer therapies company ever to exist.
Help me to save those who truly seek your peace! I really really need to money, now to help those less fortunate and to have the resources available to help.
AMEN

PS Dear friends, I am catholic, but the one God of all faiths is universal and listens to whats in our hearts. With every breathe in, feel his strength and courage and with every exhale thank him. Get as close to your God urgently, as nothing can be achieved without the deepeset and sincerest love of life.

The bible commands me to LET MY LIGHT SHINE, so I blog, I share, I care. We by necessity must build our city of survivors on the highest hill, to me thatseverest! With every success in the past, the present and the future all credit is given to God, I am simply blessed to have this experience and the gift of knowledge and the resources to show our true healing capacity. I hope all my successes, share openly there clinical results, there emotional and spiritual journeys. Nothing has ever been withheld. One day, in that honesty and candor we may together truly change the face of cancer medicine, and very very quickly.

http://csn.cancer.org/node/245835 still having psorinum, godbless my very alternative doctor mikael ndorfors and all my old friends on CSN, still taking this everyday. I believe in it, I believe in everything I do, thats alot. love and hugs Pete. You guys are never out of my prayers, and I do sneak a peak occaisionally. Getting banned, was the best thing, now I not only work for these doctors, I am setting up a cancer services empire, if I live I will succeed. Deep down still the same old pete, maybe a bit more extreme, a bit more grateful, a bit more wiser.

I needed to try everything in Australia, that allowed me to leave for Germany seeking my miracle.

Oh and the method of benefit from psorinum 6x, the smallest antigens are needed to stimulate the immune cells of the tonsil. Some believe, diets unimportant, everything we do, influences our immune system, directed wisely we can elimenate colorectal tumours. Who knows for how long my miracle will, continue, I cannot get tumour free, but I have no pain, amazing energy and power and confidence that grows by the day.

If I live, maybe my dream is possible, if I die, well Gods waiting with lots of wonderful friends. Have some fun, come to germany. You will never never know if you dont have a go.

http://www.biomedcentral.com/1471-2334/14/521 MAKE THE BLOODY YOGURT AND ENJOY, HOW MANY TIMES TO I HAVE TO SAY THIS!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!

THE CANCER WORLD IS DEAF OR DEATH, MY CUSTOMERS WILL LIVE, SO WILL I, MARK MY WORDS. GOD MADE THE BUGS! MAYBE HIS GREATEST ACHIEVEMENT, OR THE HUMAN MIND OR HEART!

My 13 YEAR OLD daughter is going to build the cancer services company website, she is a good speller, which when you think about it, is another miracle in itself. My kids have faith in my therapies, I AM ALIVE and WELL.

https://www.gcmaf.eu/gcmaf-products/bravo-probiotic/ note gcmaf.eu overstates results in general and is misleading, but in the scheme of all the crap on the net, well far less so than oncologists. So they are unethical heroes driven by greed, alas that greed will save many. if you cannot honestly afford the yogurt, contact me!

Discussion

In this pilot study of undernourished adults starting ART in sub-Saharan Africa, serum levels of circulating CRP and other inflammatory biomarkers were markedly elevated prior to treatment initiation and after 12 weeks, and there was evidence that reductions in microbial translocation biomarkers, particularly LBP, accompanied reductions in inflammatory biomarkers. However, while we observed close associations between several pairs of translocation and inflammation biomarkers, there was marked heterogeneity both between and within participants. This suggests the hypothesis that microbial translocation is a primary driver of inflammation in HIV-infected adults does not adequately capture what is likely a complex interplay of factors promoting innate immune activation in malnourished adults with advanced HIV disease.

Microbial translocation in undernourished, HIV-infected adults is likely due to the combined effects of HIV enteropathy, environmental enteropathy, and malnutrition on the intestinal mucosal barrier. HIV enteropathy generally occurs in advanced disease (e.g., CD4+ T-cell count <200 cells/μl) and is characterized by changes in villous morphology, absorption, and mucosal permeability [24,25]. Mucosal T-cell depletion, particularly loss of the Th17 cells important for bacterial, fungal, and parasitic defense, in conjunction with impaired cellular tight junctions has been proposed as an underlying mechanism [13,14,26]. Environmental enteropathy is common in many tropical regions, including Zambia, and is morphologically similar to HIV enteropathy [27]. It is thought to result from a combination of recurrent, transient infections with pathogenic bacteria and altered intestinal microbiota resulting in chronic T-cell mediated enteric inflammation, malabsorption, impairment of mucosal integrity, and reduced expression of antimicrobial peptides [27-30]. Lastly, malnutrition is associated with hypoalbuminemia and bowel wall edema, impaired adaptive immune responses, and reduced mucosal integrity [18,19,31].

Recent studies suggest that interventions to alter intestinal microbiota and mucosal cellular function in comorbid malnutrition and advanced HIV disease could provide clinical benefits for these patients, though much of this research remains at an early stage. There is evidence to suggest that probiotics can alter gastrointestinal tract microbiota, with beneficial effects on mucosal immunity [32]. In the HIV-infected population, administration of probiotics and other specialized nutritional products has led to modest improvements of CD4+ T-cell counts, reduced CD4+ T cell activation, and fewer gastrointestinal disorders [33-36]. In the mouse model, glucagon-like peptide and probiotics improved intestinal integrity and reduced inflammation in obese mice [37]. Other promising non-human trials have demonstrated that vaccines may improve gastrointestinal tract immunity by recruiting IgA secreting plasma cells to the mucosa or decreasing the local HIV burden [38,39], and the use of a bovine serum immunoglobulin in adults with HIV enteropathy improved duodenal absorptive function and increased mucosal CD4+ T cell density [40].

While increased microbial translocation and systemic inflammation are both associated with poorer health outcomes in HIV infection, further research is needed to understand the clinical consequences in undernourished African patients and to determine if prior findings in US and European cohorts are applicable to this population. In a US cohort of ART-treated adults, higher serum levels of intestinal fatty acid binding protein and lower zonulin-1, both indicative of increased gut permeability, were associated with increased all-cause mortality [41]. In Italian HIV patients, serum LPS levels predicted disease progression independently of age, CD4+ T-cell count, viral load, or duration of infection, and higher circulating LPS levels after ART initiation were associated with greater CD4+ and CD8+ T-cell activation and poor CD4+ T-cell recovery [16,42]. Increased microbial translocation is also associated with dyslipidemia, insulin resistance, and increased risk of cardiovascular events in both HIV-infected and uninfected individuals [43-45], and persistently elevated CRP and other inflammationbiomarkers predispose to fatal and non-fatal cardiovascular events [46,47]. However, conclusions regarding long-term health outcomes in African populations based on these studies are not warranted given differences in populations, background disease risk, methodology, and other factors. Further epidemiologic studies are needed to determine how very high levels of both microbial translocation and inflammation affect risk for cardiovascular, metabolic and other non-communicable diseases among HIV patients in sub-Saharan Africa.

While sCD14 has been posited as a marker of microbial translocation in prior studies of HIV-infected and uninfected populations, the association between sCD14 and inflammatory markers observed in our study and prior studies should be interpreted with caution [8,9,16,48-50]. A major uncertainty is whether high circulating sCD14 levels observed in HIV patients derive from intestinal or hepatic immune cells (e.g., intestinal monocytes or Kupffer cells exposed to LPS via the portal vein) and thus reflect increased intestinal microbial transit, or whether the increased sCD14 derives from immune cells in more distant tissues and should be classified as a general biomarker of systemic inflammation [51]. This uncertainty reduces the utility of sCD14 as an indicator of microbial translocation.

Our measurements of Lac/Cr ratio were not associated with any of our serum markers of microbial translocation, suggesting that intestinal permeability as measured by this method may not represent the same epithelial defects involved in increased microbial transit. In our cohort, the median baseline Lac/Cr ratio value of 29.3 mmol/mol was approximately 3-fold higher than in healthy controls in a prior study of European adults, but considerably lower than patients with active Crohn’s disease [52]. Furthermore, we did not observe a clinically significant change in the Lac/Cr ratio over 12 weeks, which may indicate that while defenses against microbial translocation improved on ART, paracellular absorption from the gut lumen remained elevated. However, the use of the Lac/Cr ratio in HIV-infected, malnourished adults requires further validation given the chronic dehydration, potential HIV- and nutrition-related renal dysfunction, and reduced muscle mass present in this population.

Our pilot study was limited by small sample size and incomplete follow-up of some participants. The lack of both a non-malnourished, HIV-infected control group and a malnourished, uninfected control group made it impossible to explore the independent, and potentially synergistic, contributions of HIV and malnutrition to microbial translocation. The inverse association we observed between EndoCAb IgM and inflammation markers was expected based on prior sepsis studies showing that EndoCAb IgM levels vary inversely with serum endotoxin in the post-acute phase; however, we did not see any association between EndoCAb IgG and the outcomes of interest [21]. One possibility is that the EndoCAb IgG required adjustment for total IgG level, which is both high and variable in HIV infection. Future studies would also benefit from quantification of serum LPS or bacterial DNA and analysis of intestinal histology, rather than the surrogate markers of microbial translocation we used. Lastly, our study did not measure plasma HIV-1 RNA levels, which may have had independent pro-inflammatory effects and confounded our analysis, particularly if not all participants reached viral suppression after 12 weeks of treatment.

Conclusions

Our findings suggest that excessive microbial translocation across the bowel wall contributes to the high levels of systemic inflammation observed in undernourished adults with advanced HIV disease in sub-Saharan Africa. A high degree of translocation is likely due to the compounding effects of HIV enteropathy, environmental enteropathy, and malnutrition on mucosal barrier integrity and local immune defenses. Given the known adverse effects of heightened inflammation and microbial translocation on morbidity, mortality, and immune recovery after ART initiation, the development of interventions to improve gastrointestinal health in these patients may have important benefits for clinical outcomes.